YABASHI LIME®-f the only domestic carbon dioxide absorbent
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YABASHI LIME®-f is
a carbon dioxide absorbent
which does not use NaOH(sodium hydroxide)

It does not contain neither NoOH (sodium hydroxigen) nor KOH(potassium
inhabits the production of CO (carbon oxide) and Compound A.
A singlepackage contributes to the reduction of waste as well.
What is Yabashi Lime-f ?
YABASHI LIME®-f isa new type of carbon dioxide absorbent which“does not use NaOH (sodium hydroxide)”.An anesthetic can be given safely because “toxic degradation products of anesthesias would not be generated.”Morever“special processed 1L carton”is adopted for its package, which is excellent in shading, seal-ability, and convenience.
YABASHI LIME®-f is the only one domestic carbon dioxide absorbent for medical institution. We aim to respond the desire of Japanese medical personnel.

We also handle industrial soda lime.
3 Features of Yabashi Lime-f
High safety
The safe CO2absorbent to support a safe anesthesia.
High absorbability

Special shape and special components enables high absorption capacity.
Easy to use product design Achieved both capacity and easy handing as well.
High Safety
►CO (Carbon Monooxide) Generation Test
※In-house model experiment
Generally abnormal heat under dry condition makes SODA LIME to react with inhalation anesthesia to generates CO. But YABASHI LIME-f is NaOH free, so it does not generate CO even in case of the absorbent getting dried by accident.
※Please do not dry the absorbent. If so, the absorption capacity will be drastically reduced.
Desflurane 3vol% CO2 Absorbent0% Reaction Temperature 80℃ Reaction Time 3minis
►Compound A Generation Test
YABASHI LIME -f does not contain NaOH, major cause to degrade Sevoflurane, thus it does not generate Compound A unlike other general SODA LIME. It will be especially effective in the low flow anesthesia where Compound A is suceptible to be generated.
※ Compound A = fluoromethly-2,2-difluoro-1-( trifluoromethyl ) vinyl ether
※The measure method of Compound A has been guided by Maruishi Pharmaciutical Co., Ltd.
Flow Vol.6L(Start) → 0.5L → 6L(End) Sevoflurane Conc.2%
▶Temperature Test in the Canister
※In-house model experiment
SODA LIME generates a large amount of heat upon carbon dioxide absorption, but YABASHI LIME -f is free of NaOH which is strong alkaline, so that it mitigate temperature rise in a canister. It is especially suitable for the improvement of safety in the low flow anesthesia where the heat is suceptible to accumulated.
High Absorbability
►About Product Shape
Our unique technology enables special shape of the trifid petals. The ideal absorbent has been developed with properties such as very strong, hard to pulverizes and porus to have good absorption capacity.Moreover, the particle size is large so that it can be used for various anesthesia apparatus and lung function measuring instruments.
►Micro-Pore Distribution and Porus Volume
※In-house model experiment
YABASHI LIME -f (base) has achieved high absorption capacity with its special shape with high specific surface area and special composition. In comparison with general SODA LIME containing NaOH, it has more than satisfactory absorption capacity.
Specific surface areaSpecific surface area
(㎠/g)(㎡/g)
YabashiLime-f25.20.117
SodaLime A15.30.074
SodaLime B10.00.047
LimeC7.50.037
►Durability Test
※In-house model experiment
High absorption capacity is achieved by its special shape providing high specific surface area and special composition. In comparison with general SODA LIME containing NaOH, it has more than satisfactory absorption capacity.
Easy to Use Product Design
▶Pulverization Rate Measurement
※In-house model experiment
With our unique technology, YABASHI LIME -f has realised higher specific surface area and strength with its special shape. Suppressing pulverization strongly, and hence it solves various problems such as contamination into equipments.
▶Supports Various Machines
Its particle size is large (max. diameter 4mm), so that it hardly pulverizes. So it can be used for a canister of various anesthesia apparatus and lung fintion measuring apparatus at ease.
▶Colour Change Before/After Use
Colouring appears uniformly so that it is easy to recognise visually. It is made hard to go back in colour, thus it is safe to use.
※We recommend to use a CO2 Monitor for judging when to change the absorbent.
Frequently Asked Questions
Q1.
Is “YABASHI LIME-f ” same as “SODA LIME” ? Tell me the difference between them.
A1.
“SODA LIME” is mixture of around 5 % of NaOH, over 70 % of Ca(OH)2 and 12~18% of water. It is called SODA LIME after Na (soda) and Ca (lime).
“YABASHI LIME-f” is NaOH free, so it is not same as SODA LIME exactly. However its function is more than SODA LIME, so you can take it the improved product of SODA LIME as a carbon dioxide absorbent for anesthetic.

Q2.
Q2. 「YABASHI LIME-f 」has turned to blue-violet color. Is this all right ?
A2.
In case of such a canister described in the below illustration, where exhaled breath goes through the layer of carbon dioxide absorbent from “in upward direction” , upper face of absorption layer sometimes turns to blue-purple color because the surface of absorbent granules temporarily get dry for the influence of reaction heat of absorbent or ventilation. So it doesn’t mean exhaustion of absorbent.
This coloring will be faded out by the internal moving or redistribution of water. It is no problem for its absorption capacity. Please keep using as it is.
※Note
(If you don’t know about the flow direction and the proper fill volume of the using caster of anesthesia apparatus, please confirm on the specification of anesthesia apparatus or the maker of it )
References
■Literature
・Anesthesiology 2004;101:531-3
「Acute Respiratory Distress Syndrome after an ExothermicBaralyme®-SevofluraneReaction」
・Anesth Analog 2000;91:446-450
「Absorption of Carbon Dioxide by Dry Soda Lime Decreases Carbon Monoxide Formation from Isoflurane Degradation」
・Anesthesiology 1994;80:556-565
「Toxicity of Compound A in rats: Effect of a 3-hour administration」
・Anesth Analog 1996;82:770-774
「Metabolism of Compound A by Renal Cysteine-S-Conjugate p-LyaseIs Not the Mechanism of Compound A-Induced Renal Injury in the Rat」
・Anesth Analog 1995;80:1187-93
「Carbon Monoxide Production from Degradation of Desflurane, Enflurane, Isoflurane, Halothane, and Sevofluraneby Soda Lime and Baralyme®」
・BMC Anesthesiology 2005,5:6
「Carbon monoxide production from five volatile anesthetics in dry sodalimein a patientmodel:halothane and sevofuranedo produce Carbon monoxide;temperatureis a poor predictor of carbon monoxide production」
・The Japanese journal of medical instrumentation Vol,75,No.8(2005) (17)
“Carbon dioxide absorption apparatus (Canister and carbon dioxide absorbent)”
・Anesthesia vol49 No.5 (2000) (P504~508)
“Inner circuit concentration of new carbon dioxide absorbent (SPHERASORB®) and compound A”
・Anesthesia vol48 extra number (1999) (P172~179)
“Metabolism & toxicity of anesthetics”
・Journal of Society of InoganicMaterials, Japan 16,49-54(2009)
“Prevention and suppression of highly pathogenic avian influenza by lime”

■Notes
・PFSB/ELD Notification No.0906001・ PFSD/Safety Division (SD) Notification No.0906001

■YABASHI LIME related materials etc.
・Anesthesiology 2008;64:287-292
「Performance of four carbon dioxide absorbents in experimental and clinical settings.」
・The 28th the Japan Society for Clinical Anesthesia Ⅲ-P-05  
“Practical use study for new domestic CO2 absorbent and my personal view for consumption degree indicator”
Takano Hospital Anesthesiology Toru Morioka
・The28th the Japan Society for Clinical Anesthesia Ⅲ-P-66
“The characterization of third generation soda lime”
Sapporo Medical College Anesthesiology Kazuya Takahashi and others
・the Japan Society for Clinical Anesthesia Journal Vol.29 No.4:500-505, 2009
“Practical use study for new domestic CO2 absorbent and my personal view for consumption degree indicator”
Takano Hospital Anesthesiology Toru Morioka
・The 28th Meeting of JSTA.
Development and Shftning of Carbon Dioxide Absorbents:
Toru Sato, Prof emeritus, Tottori Univ.  http://www.jsta.net/pic/yabashilime.pdf 
・CLINIC NOTE(interzoo) 2011 Sep,No.74 :39-43
“Safety of new carbon dioxide absorbent ”YABASHI LIME-f” on Isoflurane anesthesia”
Sagamihara Primo Animal Hospital Katsuaki Nishihara
・The 59th Japanese Society of Anesthesiologists P1-58-3
“Study on the improvement of coloring power of ”YABASHI LIME-f”
Gifu University Hospital Kiyoshi Nagase
・The 59th Japanese Society of Anesthesiologists P1-40-4
“Measuring comparative study of Compound A between existing carbon dioxide absorbent and a new carbon oxide absorbent which doesn’t generate it in Sevoflurane low flow anesthesia”
Toyama Municipal Hospital Takuro Nakanishi
・The 23th Congress of Japan Association of Clinical Engineers O21-5
“Benchmark of carbon dioxide absorbent for anesthesia”
Hyogo Medical College Clinical Engineer Course Daiki Tawa
・The 60th Japanese Society of Anesthesiologists P2-10-6
“Study for carbon oxide (CO) generated in the reaction between carbon dioxide absorbent and desflurane ”
Nagoya University Hospital Anesthesiology Takahiro Ando, Ayuko Suga, Shougo Suzuki, Yoko Arakawa, Kimitoshi Nishiwaki
・Clinical Engineering Vol.26 No5 p477-485 2015  
Carbon Dioxide Absorbebts- Soda lime and New others.  
Tottori University Prof emeritus Toru Sato

■Thanks
We deeply appreciate Maruishi Pharmaceutical who have cooperated and supervised on the measurement of Compound A.